# title
Effect on fatal ICH comparing alteplase vs. placebo 3-4.5 hours after stroke

# citeAs
Effect on fatal ICH comparing alteplase vs. placebo 3-4.5 hours after stroke [Database Entry: FHIR Evidence Resource]. Contributors: Brian S. Alper, MD, MSPH [Authors/Creators]. In: Fast Evidence Interoperability Resources (FEvIR) Platform, FOI 560158. Revised 2026-04-13. Available at: https://fevir.net/resources/Evidence/560158. Computable resource at: https://fevir.net/resources/Evidence/560158#json.

# relatesTo[].targetReference.display
25106063 Effect of treatment delay, age, and stroke severity on the effects of intravenous thrombolysis with alteplase for acute ischaemic stroke: a meta-analysis of individual patient data from randomised trials.

# variableDefinition[].intended.display
Patients treated 3-4.5 hours after acute stroke

# variableDefinition[].description
Patients treated within 0-3 hours after acute stroke

# variableDefinition[].intended.display
GroupAssignment: Alteplase vs. no alteplase (3-4.5 hours after stroke)